Doubling the power of gene therapies

Discover the essence of biotechnological innovation with our meticulous plasmid DNA manufacturing services in Thailand.

Twogene Plasmid DNA Manufacturing services

Turn precise genetic craftsmanship into pioneering advancements and accelerate your R&D and clinical processes. Twogene operates a proprietary fast-turnaround pDNA manufacturing capability with state of the art material and facility. From 1L to 30L batches in research grade and from 15 to 500L batches in GMP-grade, contact us to know more.

Our Innovative DNA production

Plasmid for AAV

From preclinical to commercial stages, we manufacture specific DNA plasmids for AAV gene therapy on our research grade lines and our GMP-grade production lines.

Messenger RNA

Derived from state-of-the-art fermentation and purification processes, we provide high-yield and purity linearized pDNA, validated according to your quality criteria.

Recombinant proteins

With a wide range of fermentation capacities, we are your partner of choice to produce proteins of therapeutic interest from discovery to clinical stages.

Twogene Blueprint for Success

At Twogene, we put our customers’ interests at core. We make the production of pDNA more robust, faster and more cost-effective.

Our team of experienced engineers, scientists and pharmacists have developed, following intensive R&D, a GMP-compliant proprietary process which enables:

Our facility also provides great flexibility in terms of scale from research-grade [1L to 30L] to cGMP grade productions [15L to 500L]. 

Twogene Plasmid DNA Services

Twogene offers one-stop service from your sequence to an optimised manufacturing process

Upon your request, we can optimize your pDNA sequence to reach the highest yields. After cloning the sequence in our bacterial production system and checking its accuracy by NGS, we develop optimise our lab-scale process to your research-grade pDNA. 

Depending on your requirements, we can use our wide range of bioreactors to produce batches between 1L to 30L.

At Twogene, we harness the production of complex DNA sequences to deliver GMP compliant plasmid DNA for gene therapy and vaccine companies. 

Our 2000 sqm production facilities equipped with grade C And D cleanroom environments allows for small-scale GMP capabilities for manufacturing of Master and Working cell banks as well as large-scale GMP compliant production of pDNA and proteins in top-of-the range stainless steel bioreactors of 15, 50 and 500L.

Quality is at the core of our DNA, our facility and QA processes are cGMP audited against international GMP guidelines and the Pharmaceutical Inspection Co-operation Scheme (PIC/S).

Our plasmid DNAs are thus suitable for preclinical, clinical and commercial stages worldwide. 

Our 2000 sqm production facilities equipped with grade C And D cleanroom environments allows for small-scale GMP capabilities for manufacturing of Master and Working cell banks.

Twogene GMP compliant online monitoring system then keep the precious cell banks safe and cool in our fully validated -80 degrees environment.

Elevate your research with our Recombinant Protein Expression Service, designed for precision and versatility.

Whether you require microbial fermentation or mammalian cell culture, we cater to your needs.

Harness the power of cutting-edge technology and trust our expert team to deliver customized, high-quality proteins tailored to your specifications, from small-scale projects to expansive 500L endeavors.

Streamline your research journey and unlock the potential of your experiments with our comprehensive Recombinant Protein Expression Service.

Twogene offers one-stop service from your sequence to an optimised manufacturing process

Upon your request, we can optimize your pDNA sequence to reach the highest yields. After cloning the sequence in our bacterial production system and checking its accuracy by NGS, we develop optimise our lab-scale process to your research-grade pDNA. 

Depending on your requirements, we can use our wide range of bioreactors to produce batches between 1L to 30L.

At Twogene, we harness the production of complex DNA sequences to deliver GMP compliant plasmid DNA for gene therapy and vaccine companies. 

Our 2000 sqm production facilities equipped with grade C And D cleanroom environments allows for small-scale GMP capabilities for manufacturing of Master and Working cell banks as well as large-scale GMP compliant production of pDNA and proteins in top-of-the range stainless steel bioreactors of 15, 50 and 500L.

Quality is at the core of our DNA, our facility and QA processes are cGMP audited against international GMP guidelines and the Pharmaceutical Inspection Co-operation Scheme (PIC/S).

Our plasmid DNAs are thus suitable for preclinical, clinical and commercial stages worldwide. 

Our 2000 sqm production facilities equipped with grade C And D cleanroom environments allows for small-scale GMP capabilities for manufacturing of Master and Working cell banks.

Twogene GMP compliant online monitoring system then keep the precious cell banks safe and cool in our fully validated -80 degrees environment.

Elevate your research with our Recombinant Protein Expression Service, designed for precision and versatility.

Whether you require microbial fermentation or mammalian cell culture, we cater to your needs.

Harness the power of cutting-edge technology and trust our expert team to deliver customized, high-quality proteins tailored to your specifications, from small-scale projects to expansive 500L endeavors.

Streamline your research journey and unlock the potential of your experiments with our comprehensive Recombinant Protein Expression Service.

Ready To Speed Up Your Development Programs?